Structural Chemistry Group

Research activities

Transporting protein as drug carrier (transcobalamin and bioconjugates of vitamin B12)

Viral proteins and antiviral drugs (HIV protease and peptidomimetic inhibitors; HCV with cryoglobulinemia and vaccine development)

Protein folding and aggregation: metals and biomolecules in protein conformational diseases (b2-microglobulin and amyloid fibril formation)

Enzymatic catalysis in protein crystals (trapping of reaction intermediate as in maltodextrin phosphorylase)

Artificial proteins (catalytic active four helix bundles from denovo design and miniaturized eme proteins)

Supramolecular chemistry (Nanocapsules for drug delivery, sensors, etc.)

Metal complexes of pharmacological interest

Mono- and poly-nuclear complexes of catalytic interest

Cobalamins and models of vitamin B12 system

EXAFS spectroscopy